Z-LEVD-FMK
Product Overview
Product Name: Z-LEVD-FMK
Alternate Name/Synonyms: Z-LEVD-FMK, Z-LEVD-fluoromethylketone, Caspase-4 Inhibitor (fluoromethylketone)
Description: A synthetic peptide that irreversibly inhibits activity of LEVD-dependent caspases (e.g., caspase-4). The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Peptide Sequence: Z-Leu-Glu(OMe)-Val-Asp(OMe)-FMK
Appearance: Lyophilized solid
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₃₁H₄₅FN₄O₁₀
Molecular Weight: 652.7
Purity: Single spot by TLC
Solubility:DMSO (20 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1
InChi: InChI=1S/C31H45FN4O10/c1-18(2)14-23(35-31(43)46-17-20-10-8-7-9-11-20)29(41)33-21(12-13-25(38)44-5)28(40)36-27(19(3)4)30(42)34-22(24(37)16-32)15-26(39)45-6/h7-11,18-19,21-23,27H,12-17H2,1-6H3,(H,33,41)(H,34,42)(H,35,43)(H,36,40)
InChi Key: WGJLXPZGHLANRB-UHFFFAOYSA-N
PubChem CID: 44135220
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.