Acridine Orange
AO, 3,6-bis(Dimethylamino)acridine, HCl
A cell-permeable, cationic fluorescent dye that interacts with DNA and RNA by intercalation or electrostatic attractions. When bound to DNA, it is spectrally very similar to fluorescein, with an excitation maximum at 502 nm and an emission maximum at 525 nm. Upon association with RNA, the excitation maximum shifts to 460 nm and the emission maximum shifts to 650 nm (red). Often used to measure single- and double-stranded DNA and RNA in the diagnosis, classification, and prognosis of many neoplasms. A very versatile fluorescent stain used in histochemistry and cytochemistry that can be used to provide information about the in situ content, molecular structure, and conformation of many nucleic acid-containing cell constituents.
產(chǎn)品信息
Form  Burnt-orange solid
Molar mass  301.8
Protect from Light  是的
Hygrocopic  是的
Purity  ≥98% by HPLC
Solubility  DMF, EtOH, or H2O
Chemical formula  C17H20ClN3
RTECS  AR7601000
CAS number  65-61-2
商店和運(yùn)輸信息
Storage  +15°C to +30°C
Ship  Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic
安全標(biāo)示
S Phrase  S: 36
Wear suitable protective clothing.
R Phrase  R: 20/21/22-40
Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect.