Apoptosis Inhibitor
M50054, 2,2′-Methylenebis(1,3-cyclohexanedione)
A cell-permeable inhibitor of apoptosis induction (IC50 = 67 µg/ml in FasL-stimulated WC8 cells, 130 µg/ml in etoposide-stimulated U937 cells). Effects attributable to the inhibition of caspase-3 activation but does not directly inhibit caspase-3 even at 1 mg/ml.
產(chǎn)品信息
Form  Off-white solid
Primary Target  apoptosis induction
Primary Target IC50  67 µg/ml in FasL-stimulated WC8 cells, 130 µg/ml in etoposide-stimulated U937 cells
Molar mass  236.3
Protect from Moisture  是的
Packaged under inert gas  是的
Cell permeable  是的
Purity  ≥95% by HPLC
Solubility  DMSO or EtOH
Chemical formula  C13H16O4
CAS number  54135-60-3
商店和運輸信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Standard Handling