Binucleine 2
N′-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide, Aurora Kinase Inhibitor VII
A cell-permeable pyrazolo compound that inhibits cytokinesis function of the Aurora B kinase pathway. Inhibits Histone H3 phosphorylation on Ser10 in mitotic Drosophila Kc167 cells at 20 µM, while inactive in mammalian systems. Does neither function as a general kinase inhibitor nor inhibit Cdk-dependent entry into mitosis.
產(chǎn)品信息
Form  Brown solid
Molar mass  291.7
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or MeOH
Chemical formula  C13H11ClFN5
CAS number  220088-42-6
商店和運(yùn)輸信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Carcinogenic / Teratogenic