Compound 401|正品原裝
產(chǎn)品信息： 
Form  Beige solid 
Protect from Light  是的 
Packaged under inert gas  是的 
Purity  ≥95% by HPLC 
Chemical formula  C16H15N3O2 
CAS number  168425-64-7 
Storage  +2°C to +8°C 
Ship  Ambient Temperature Only
Standard Handling 
產(chǎn)品說明：
A cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (IC50 = 5.3 µM). Exhibits much reduced or no activity against 43 other commonly studied kinases, including PI 3-K, ATM, and ATR. Shown to induce apoptosis and inhibit mTOR-dependent growth in TSC1-/- murine embryo fibroblasts.