16,16-Dimethyl Prostaglandin E2
9-Oxo-11α,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid, dmPGE2
A cell-permeable and orally available synthetic PGE2 (Cat. No. 538904) 16,16-dimethyl derivative that exhibits similar biological activity as PGE2 as an EP receptor agonist both in in vitro and in in vivo, while being more resistant to PGDH metabolism. Shown to amplify wnt activity through cAMP/PKA-mediated regulation of cellular β-catenin protein stability during vertebrate development and organ regeneration.
產(chǎn)品信息
Form  Liquid
Formulation  Supplied as a solution in methylacetate (1 mg/100 µL)
Molar mass  380.5
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or EtOH
Chemical formula  C22H36O5
CAS number  39746-25-3
商店和運輸信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage  ≤ -70°C
Ship  Dry Ice Only
Flammable