Protein Synthesis Initiation Inhibitor, NSC 119889
3,4,5,6-Tetrabromofluorescein
A cell-permeable, xanthenyl compound that prevents mRNA-ribosome interaction and inhibits 5’-mediated/cap-dependent initiation of protein synthesis (>95% inhibition at 50 µM in in vitro translation assays using Krebs, rabbit reticulocyte, or E. coli S30 extract).
產(chǎn)品信息
Form  Light brown solid
Primary Target  human arginine methyl transferase
Primary Target IC50  1.41 µM
Secondary target  IC50 = 780 nM yeast arginine methyl transferase
Molar mass  647.9
Protect from Light  是的
Cell permeable  是的
Purity  ≥95% by HPLC
Solubility  DMSO or MeOH
Chemical formula  C20H8Br4O5
商店和運輸信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Irritant