Ru360
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM). Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ~10 µM of Ru360 for 30 min). Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels. Note: 1 set = 10 x 100 µg.
產(chǎn)品信息
Form  Reddish brown solid
Primary Target  blocks Ca2+ uptake into mitochondria in vitro
Primary Target IC50  184 pM
Molar mass  550.8
Protect from Light  是的
Hygrocopic  是的
Packaged under inert gas  是的
Cell permeable  是的
Purity  ≥97% by capillary electrophoresis
Solubility  deoxygenated H2O
Chemical formula  C2H26Cl3N8O5Ru2
商店和運(yùn)輸信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling