中文名稱: 姜黃素,姜黃色素 英文名稱: Curcumin,Turmeric yellow, Diferuloylmethane , 1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)- 說明: 姜黃素可用來抗菌,解毒,為橙黃色結(jié)晶粉末,味稍苦。不溶于水,溶于乙醇、丙二醇,易溶于冰醋酸和堿溶液,在堿性時呈紅褐色,在中性、酸性時呈黃色。對還原劑的穩(wěn)定性較強,著色性強(不是對蛋白質(zhì)),一經(jīng)著色后就不易退色,但對光、熱、鐵離子敏感,耐光性、耐熱性、耐鐵離子性較差。 Sigma相關(guān)產(chǎn)品資料: Sigma C7727 Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin) Synonym: Diferuloylmethane, Diferulylmethane, Natural Yellow 3, (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione CAS Number: 458-37-7 Linear Formula: [HOC6H3(OCH3)CH=CHCO]2CH2 Molecular Weight: 368.38 Colour Index Number: 75300 Beilstein Registry Number: 2306965 EC Number: 207-280-5 MDL number: MFCD00008365 PubChem Substance ID: 24892983 Description Biochem/physiol Actions A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Properties vapor density 13 (vs air) assay ≥80% (Curcumin) ≥94% (curcuminoid content) solubility ethanol: 1 mg/mL DMSO: 11 mg/mL 0.5 M NaOH: soluble (then immediately diluted in PBS) Gene Information human ... APP(351), CYP1A2(1544) storage temp. −20°C Safety Hazard Codes Xi Risk Statements 36/37/38 Safety Statements 26-36 WGK Germany 2 RTECS MI5230000 備有大量現(xiàn)貨! |