Cytochrome P-450 inhibitor. Inhibits cytochrome P-450-dependent arachidonate metabolism (90% at 50 µM). Calcium antagonist. Blocks glibenclamide-sensitive K+ channels (IC50=4.4mM). Inhibits platelet thromboxane synthesis and stimulates endothelial cell prostacyclin production. Potentiates the effects of many drugs in vivo.
Product Specification
Alternative Name:Proadifen
Formula:C23H31NO2 . HCl
MW:389.9
CAS:62-68-0
Purity:≥95% (TLC)
Appearance:White solid.
Hazard:HARMFUL.
Solubility:Soluble in water (25mg/ml) or 100% ethanol.
Long Term Storage:Ambient
Use/Stability:Store, as supplied , at room temperature for up to 1 year.
Handling:Hygroscopic.