Primocin™
Antimicrobial for Primary Cells
Primocin™ is an antibiotic formulation specifically designed to protect primary cell lines from cell culture contaminations. Primocin™ is active against both Gram+ and Gram- bacteria, mycoplasmas and fungi. Primocin™ is the first formulation to offer complete protection against microbial contaminants. There is no need to add Pen/Strep.
Primocin™ is non-toxic to primary cells. It acts on targets found only in micro-organisms. Bacterial targets are the DNA gyrase and the prokaryotic ribosomal subunits, 30S and 50S. The fungal target is ergosterol, a molecule only found in the cell membrane of fungi and yeasts.
Primocin has been used successfully in many primary cells, including mouse- and human-tumor derived cell lines [1], embryonic cells [2] and induced pluripotent stem cells [3-6].
Sterile water soluble solution
Recommended working concentration: 100 μg/ml
One ml Primocin™ is enough to treat 500 ml medium
Shipped at room temperature