中文名:新生霉素
英文名:Novobiocin; Cathocin; Albamycin;Novobiocin sodium salt;Novobiocin sodium
用途:抗菌作用與青霉素G、紅霉素相似,主要抗革蘭氏陽性菌,金葡菌的最小抑菌度MIC一般為1~4μg/ml,對耐青霉素的金葡菌或對其他抗生素已產生耐藥性的菌株依舊敏感。對革蘭氏陰性菌除嗜血桿菌外,大都不敏感,對立克次體、真菌、病毒無效。
SIGMA相關資料如下:
Sigma-Aldrich N6160 Novobiocin sodium
meets USP testing specifications
Synonym: Novobiocin sodium salt
CAS Number: 1476-53-5
Linear Formula: C31H35N2NaO11
Molecular Weight: 634.61
Beilstein Registry Number: 3892910
EC Number: 216-023-6
MDL number: MFCD00066541
PubChem Substance ID: 24897774
Description
Application For the production of positively supercoiled plasmid DNA.1 Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase.2 Inhibitor of retrovirus RNA-dependent DNA-polymerase.3
Biochem/physiol Actions Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II.
Antimicrobial spectrum: Gram-positive bacterial.
性質
suitability meets USP testing specifications
storage temp. 2-8°C