名稱:Rosiglitazone,羅格列酮
別名: 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, Rosiglitazone
產(chǎn)地:sigma
貨號:R2408
規(guī)格:10mg
CAS號 122320-73-4
分子量 357.43
保存溫度:2-8°C
說明:
羅格列酮是一種強有力的興奮劑,與一個半中毒的PPARγ43海里為人類受體。這是治療糖尿病藥、工作作為胰島素增感劑通過結(jié)合到PPARγ受體在脂肪細胞,使細胞對胰島素的反應更迅速。
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.