
細胞松弛素 D Cytochalasin D
產(chǎn)品編號:C8273
產(chǎn)品名稱:細胞松弛素 D Cytochalasin D
供應商:Sigma
規(guī)格: 1MG
目錄價:2301
CAS編號:22144-77-0
產(chǎn)品編號 C8273
CAS號 22144-77-0
細胞松弛素 D Cytochalasin D
from Zygosporium mansonii, ≥98% (TLC and HPLC), powder
別名: 松胞菌素 D
經(jīng)驗分子式(希爾表示法) C30H37NO6
分子量 507.62
Biochem/physiol Actions
肌動蛋白聚合化的強效抑制劑;破壞肌動蛋白微絲;活化 p53 依賴性途徑;抑制平滑肌收縮;抑制胰島素刺激的糖轉運。
Cell permeable fungal toxin; potent inhibitor of actin polymerization. Disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. Inhibits smooth muscle contraction. Inhibits insulin-stimulated, but not basal, transport of glucose.
biological source from Zygosporium mansonii
assay ≥98% (TLC and HPLC)
form powder
solubility DMSO: soluble
ethanol: soluble
storage temp. -20度