RELM-b, human recombinant
Colon and small intestine-specific cysteine-rich protein
Product Overview
Alternate Names / Synonyms: Human RELMb, RELMb, h-RELMb, rh-RELMb, recombinant human RELMb, RELM beta, RELM-beta, recombinant RELM-beta, RELM
Gene Symbol: RETNB
Accession #: Q9BQ08
Gene ID: 84666
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 11.0 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: ≥95%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Test in process
Reconstitution Instructions: Reconstitute to 1 mg/ml with sterilized dH₂O. Pipet to dissolve the protein pellet completely.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: Human RELM β (Resistin-like molecule β/FIZZ2) is a new member to the family of adipocyte secreted proteins called adipocytokines. This family includes the RELM α, RELM β and Resistin molecules. Interestingly, RELM β and Resistin share similar characteristics such as an additional cysteine residue within the variable N-terminal region and are both homodimeric proteins. However, the RELM β is expressed only in the gastrointestinal track; especially the colon, while the Resistin and RELM β are secreted exclusively by adipocytes. Currently, the biological function of these proteins, as well as their molecular targets is largely unknown. Recombinant Human RELM β is a disulfide-linked homodimer with a total molecular weight of 11.0 kDa, consisting of 90 amino acid residue chains.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.