Galectin-3, human recombinant
A protein involved in cell growth and differentiation, cell cycle, and apoptosis.
Product Overview
Alternate Names / Synonyms: Human Galectin-3, Galectin-3, Galectin3, Galectin 3, h-Galectin-3, rh-Galectin-3, recombinant human Galectin-3, Galectin3, recombinant Galectin-3
Gene Symbol: LEG3
Accession #: P17931
Gene ID: 3958
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 0.5X PBS, pH 7.2.
Molecular Weight: 26.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galactin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 can function intraCellularly in controlling cell cycle and preventing T-cell apoptosis, and also extraCellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Recombinant Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues, but no disulfide bonds.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.