Apamin, Bee Venom
Polypeptide neurotoxin known to pass through the blood-brain barrier. Blocks the AHP-type Ca2+-activated K+ channel; does not block the TEA and voltage-sensitive Ca2+-activated K+ channel. Reported to induce neurodegeneration of Purkinje cells in rat brain. Known to induce the secretion of prolactin in a dose-dependent manner.
產(chǎn)品信息
Peptide Sequence  H-Cys¹-Asn-Cys3-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys¹¹-Ala-Arg-Arg-Cys¹5-Gln-Gln-His-NH2 (disulfide bonds: 1 → 11; 3 → 15)
Form  White solid with dark tan cast
Molar mass  2027.3
Hygrocopic  是的
Purity  ≥98% by HPLC
Solubility  5% Acetic Acid
Chemical formula  C79H131N31O24S4
RTECS  CD6899900
CAS number  24345-16-2
Merck USA index 14, 725
商店和運(yùn)輸信息
Storage  -20°C
Ship  Ambient Temperature Only
Harmful
安全標(biāo)示
S Phrase  S: 36
Wear suitable protective clothing.
R Phrase  R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed.