PD 169316
4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM). Inhibition of p38 MAP kinase by PD 169316 blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines.
產(chǎn)品信息
Form  Orange-yellow solid
Primary Target  p38 MAP kinase
Primary Target IC50  89 nM
Molar mass  360.3
Protect from Light  是的
Cell permeable  是的
Purity  ≥98% by HPLC
Solubility  DMSO
Chemical formula  C20H13FN4O2
CAS number  152121-53-4
商店和運(yùn)輸信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling