PKCβ Inhibitor
3-(1-(3-Imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione
An anilino-monoindolylmaleimide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of PKCβ isozymes (IC50 = 5 nM and 21 nM for human PKCβII and βI) and displays greater selectivity over PKCα, γ,& ε (IC50 = 331 nM, > 1 µM, and 2.8 µM, respectively).
產(chǎn)品信息
Form  Orange solid
Primary Target  PKCβII, βI
Primary Target IC50  5 nM, 21 nM
Secondary target  PKCα, γ, ε (IC50 = 331 nM, > 1 µM, 2.8 µM, respectively)
Molar mass  411.5
Protect from Light  是的
Packaged under inert gas  是的
ATP Competitive  是的
Purity  ≥90% by HPLC
Solubility  DMSO
Chemical formula  C24H21N5O2
CAS number  257879-35-9
商店和運輸信息
Storage  +2°C to +8°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling