RNA-Editing Ligase 1 Inhibitor, NSC 45208
4,5-Dihydroxy-3-(1-naphthyldiazenyl)-2,7-naphthalenedisulfonic acid, disodium salt, dihydrate, REL1 Inhibitor
This product has been discontinued.
A sulfonated azo dye, initially identified by a Trypanosoma burcei RNA-editing ligase 1 (TbREL1) crystal structure-based inhibitor screening, is shown to inhibit TbREL1 activity (IC50 = 1.95 µM) by targeting the enzyme's ATP binding pocket. V1 is less potent against T4 phage RNA ligase 2 and human DNA ligase IIIβ (IC50 = 3.53 and 27.49 µM, respectively).
產(chǎn)品信息
Form  Dark red solid
Molar mass  590.48
Protect from Light  是的
Hygrocopic  是的
Packaged under inert gas  是的
Purity  ≥95% based on elemental analysis
Solubility  DMSO or H2O
Chemical formula  C20H12N2Na2O8S2 • 4H2O
商店和運輸信息
Storage  +15°C to +30°C
Ship  Ambient Temperature Only
Standard Handling