N-WASP-Inhibitor, 187-1
cyclo(LKDFDPDFLFDPLQ)2
A 14-amino acid cyclic peptide that potently blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-induced actin assembly in Xenopus egg cytoplasmic extract (IC50 ~ 2 µM). Shown to directly bind to neural Wiskott Aldrich syndrome protein (N-WASP) with high-affinity, and prevent the activation of actin-related protein 2/3 (Arp2/3) complex by inhibiting the interaction between N-WASP and Arp2/3.
產(chǎn)品信息
Peptide Sequence  cyclo(LLys-DPhe-DPro-DPhe-LPhe-DPro-LGln)2
Form  White lyophilized solid
Formulation  Supplied as a trifluoroacetate salt.
Molar mass  1784.1
Hygrocopic  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or Acetic Acid
Chemical formula  C96H122N18O16
商店和運輸信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling