Wnt Agonist
2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine, Wnt Pathway Activator I
A cell-permeable pyrimidine compound that acts as a potent and selective activator of Wnt signaling without inhibiting the activity of GSK-3β (IC50 > 60 µM). Shown to mimic the effect of Wnt and induce β-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells), and cause substantial head defects during Xenopus embryonic development. Also available as a 10 mM solution in DMSO (Cat. No. 681664).
產品信息
Form  Yellowish sticky solid
Molar mass  350.4
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or EtOH
Chemical formula  C19H18N4O3
CAS number  853220-52-7
商店和運輸信息
Storage  +2°C to +8°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling