貨號	產(chǎn)品名稱	廠家	規(guī)格	單價	詳細(xì)	訂購
C3662	Cyclosporin A (環(huán)胞霉素A,環(huán)孢霉素A)	Sigma	5MG	1250	詳細(xì)查看	訂購
C3662	Cyclosporin A (環(huán)胞霉素A,環(huán)孢霉素A)	Sigma	10MG	2280	詳細(xì)查看	訂購

英文名:Ciclosporin A,CsA,Cs-A,CY-A,Sandimmune,Ciclosporin,Cyspin.
中文名:環(huán)孢多肽A;環(huán)孢靈;環(huán)孢霉素A;賽斯平;山地明 ,環(huán)孢素,新山地明,環(huán)孢素A
Sigma相關(guān)產(chǎn)品資料:
Sigma C3662 Cyclosporin A
from Tolypocladium inflatum, ≥95% (HPLC), solid
Synonym:Antibiotic S 7481F1, Cyclosporine
CAS Number:59865-13-3
Linear Formula:C62H111N11O12
Molecular Weight:1202.61
Beilstein Registry Number:3647785
MDL number: MFCD00274558
PubChem Substance ID:24278028
Description
Biochem/physiol Actions
 A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from  mitochondria.
Properties
biological sourcefrom Tolypocladium inflatum
assay≥95% (HPLC)
form solid
color white
solubility dichloromethane: 10 mg/mL
ethanol: 10 mg/mL
DMSO: 50 mg/mL
chloroform: 6 mg/mL
H2O: insoluble
Gene Information human ... PPP3CA(5530), PPP3CB(5532), PPP3CC(5533), PPP3R1(5534), PPP3R2(5535)
storage temp. 2-8°C