利福平 Rifampicin
中文名:利福平,甲哌利福霉素,力復(fù)平、利米定
英文名:Rifampicin ,RFP, 3-[[(4-甲基-1-哌嗪基)亞氨基]甲基]-利福霉素
CAS No. 13292-46-1
用途: 對(duì)結(jié)核桿菌和其他分支桿菌(包括麻風(fēng)桿菌等),在宿主細(xì)胞內(nèi)、外均有明顯的殺菌作用。對(duì)腦膜炎球菌、流感嗜血桿菌、金黃色葡萄球菌、表皮鏈球菌、肺炎軍團(tuán)菌等也有一定的抗菌作用。對(duì)某些病毒、衣原體也有效。
Sigma相關(guān)產(chǎn)品資料:
Sigma R3501 Rifampicin
≥97% (HPLC), powder
Synonym: 3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP
CAS Number: 13292-46-1
Linear Formula: C43H58N4O12
Molecular Weight: 822.94
Beilstein Registry Number: 5723476
EC Number: 236-312-0
MDL number: MFCD00151389
PubChem Substance ID: 24899363
Description
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Biochem/physiol Actions Inhibits the assembly of DNA and protein into mature virus particles.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.
性質(zhì)
assay ≥97% (HPLC)
form powder
color orange-brown to red-brown
solubility H2O: 1.3 mg/mL (pH 4.3)
DMSO: 100 mg/mL
H2O: 2.5 mg/mL at 25 °C (pH 7.3)
storage temp. −20°C