英文名：Hyaluronidase (Ronidase)
中文名：玻璃酸酯，玻璃糖醛酸酶，玻璃樣酸酶，透明質(zhì)酸酶
說明：透明質(zhì)酸酶(hyaluronidase,HAase)是能使透明質(zhì)酸產(chǎn)生低分子化作用酶的總稱,一種能夠降低體內(nèi)透明質(zhì)酸的活性，從而提高組織中液體滲透能力的酶。
用途：為一種能水解透明質(zhì)酸的酶(透明質(zhì)酸為組織基質(zhì)中具有限制水分及其它細(xì)胞外物質(zhì)擴(kuò)散作用的成分)，用于人體能暫時(shí)降低細(xì)胞間質(zhì)的粘性，可促使皮下輸液、局部積貯的滲出液或血液加快擴(kuò)散而利于吸收，為一種重要的藥物擴(kuò)散劑。臨床用作藥物滲透劑，促進(jìn)藥物的吸收，促進(jìn)手術(shù)及創(chuàng)傷后局部水腫或血腫消散。
Simga相關(guān)產(chǎn)品資料
Sigma  H3506   Hyaluronidase from bovine testes
Type I-S, lyophilized powder, 400-1000 units/mg solid
Synonym: Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase
CAS Number: 37326-33-3
Enzyme Commission (EC) Number: 3.2.1.35  ( BRENDA  | IUBMB  )
EC Number: 253-464-3
MDL number: MFCD00131351
Description
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Biochem/physiol Actions These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
Other Notes View more information on enzymes for complex carbohydrate analysis at Unit Definition One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37°C in a 2.0 ml reaction mixture (45 minute assay).
Properties
type Type I-S
form lyophilized powder
mol wt mol wt ~55 kDa (four subunits of 14 kDa each)
storage temp. −20°C
Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements 22-24/25
WGK Germany 3